Figure 6.

Collagen production of skin explants with and without Tisseel on templated and nontemplated trilayer electrospun scaffolds over a 21-day period determined by staining for collagen with Sirius red. Results shown are mean ±SEM, (n = 3). In all cases, explants were placed on scaffolds, which were either templated or nontemplated and in half of the experiments explants were kept in place using Tisseel. █ Templated Scaffolds with Tisseel, █ Nontemplated Scaffolds with Tisseel, █ Templated Scaffolds, and █ Nontemplated Scaffolds.