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. 2020 May 14;9(4):100422. doi: 10.1016/j.imr.2020.100422

Fig. 1.

Fig. 1

MIT reduces body fat in mice. A) The effects MIT on body weight of HFD-administrated mice was shown. B) DXA images of fat show the alleviation effect of MIT on fat distribution in mice with NAFLD. C) The graph represents DXA image analysis data for the fat distribution in mice. The MIT group had the lowest increase in fat composition. D, E) The mitigating effects of MIT on total cholesterol and glucose levels in mice with NAFLD. Abbreviations: Ctrl, C57BL/6 mice fed with normal diet; DXA, dual-energy X-ray absorptiometry; HFD, C57BL/6 mice fed with high-fat diet; Met, C57BL/6 mice fed with high-fat diet, administered with metformin (17 mg/kg/day) for 8 weeks; MIT, C57BL/6 mice fed with high-fat diet and administered MIT (60 mg/kg/day) extract for 8 weeks; NAFLD, non-alcoholic fatty liver disease. *, P < 0.05 compared with HFD group; #, P < 0.05 compared with Met group.