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. 2020 May 14;9(4):100422. doi: 10.1016/j.imr.2020.100422

Fig. 6.

Fig. 6

MIT decreases non-alcoholic liver damage. A) Immunohistochemistry shows the expression of 8-OHdG and caspase 3 in the liver of NAFLD mice. B) The graph represents the number of 8-OHdG and caspase 3 immunopositive cells in panel A). Compared with the HFD group, the MIT group shows significantly attenuated non-alcoholic liver damage. Abbreviations: CV, central vein; PV, portal vein; Ctrl, C57BL/6 mice fed with normal diet; HFD, C57BL/6 mice fed with high-fat diet; Met, C57BL/6 mice fed with high-fat diet and administered metformin (17 mg/kg/day) for 8 weeks; MIT, C57BL/6 mice fed with high-fat diet and administered MIT (60 mg/kg/day) extract for 8 weeks. *, P < 0.05 compared with HFD group; #, P < 0.05 compared with MIT group. Bar size, 50 μm (magnification, 200X).