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. 2020 May 29;20:134. doi: 10.1186/s12874-020-01018-7

Table 1.

Summary of recommendations or considerations from STROBE, ROBINS-I and Sterne et al. guidelines

Recommendation Explanation STROBE ROBINS-I Sterne et al.
Patient Selection
State eligibility criteria State inclusion and exclusion criteria of study participants, including criteria concerning missing data
Report the number of individuals at each stage of the study Give reasons for exclusion at each stage
Indicate the amount of individuals discarded due to missingness at each stage of the study
Give consideration to selection bias introduced by exclusion criteria
May use a flowchart to summarise
Modelling and Covariate Selection
Covariates Detail whether included as continuous or categorical and, if relevant, detail how the quantitative covariate was categorised
Consider departures from linearity for continuous covariates and state which transformation, if any, was used
State analysis model make it clear which method will be used to model the data
Covariate Selection describe the procedure used to reach the final model
this includes, but is not restricted to, missing data imputation, transformation of covariates, interactions between covariates or inclusion of covariates for a priori reasons
Results Provide unadjusted estimates and the final adjusted model
State the number of participants included in unadjusted and adjusted analyses
Missing Data
Report the number of participants with missing data Report this for each covariate of interest or the number of complete data for the important covariates
Give reasons for missing values
Investigate if there are key differences between those observed and those with missing data - this may be compared across exposure/intervention groups.
Missing data methods (general)
Which method was used to handle missing data? State clearly the method used
State any missing data assumptions that were made Such as whether the data are MCAR, MAR or MNAR
Sensitivity analysis Should investigate robustness of findings
Compare method with a complete-case analysis
If necessary, assess validity of methods if there are differences
Assess plausibility of missing data assumptions
Multiple Imputation
Give details of the imputation model State the software used and key settings for imputation model
State the number of imputations used
State variables included in imputation model
State how non-normal or binary covariates were handled
Were interactions in analysis model included in imputation model?
If a large fraction of data are imputed, compare observed and imputed values
Missing data assumptions Discuss if variables included in the imputation model make MAR assumption plausible
Sensitivity analyses Compare MI results with CC results
Investigate departures from MAR assumption
If necessary, suggest explanations for why there are differences in results across sensitivity analyses