Fig. 3.

BBG reduces the pool of myofibroblasts and collagen synthesis in UUO. a Graphical representation of α-SMA surface density in renal cortex. The graphic presents aligned dot plot and the mean ± SEM of 20 captured images of each kidney in the different experimental groups. * p < 0.05 vs UUO-BBG and both SHAM groups. # p < 0.05 vs UUO-V and both SHAM groups. b Representative immunostaining of the renal cortex from UUO-V group and c UUO-BBG group. d Graphical representation of α-SMA surface density in renal medulla. The graphic shows aligned dot plot and the mean ± SEM of 20 captured images of each kidney in the different experimental groups. * p < 0.05 vs UUO-BBG and both SHAM groups. e Representative immunostaining of the renal medulla from UUO-V group and f UUO-BBG group. g Graphical representation of HSP-47 surface density in renal cortex. The graphic presents aligned dot plot and the mean ± SEM of 20 captured images of each kidney in the different experimental groups. * p < 0.05 vs UUO-BBG and both SHAM groups. h Representative immunostaining of the renal cortex from UUO-V group and i UUO-BBG group. j Graphical representation of HSP-47 surface density in renal medulla. The graphic presents aligned dot plot and the mean ± SEM of 20 captured images of each kidney in the different experimental groups. * p < 0.05 vs UUO-BBG and both SHAM groups. k Representative immunostaining of the renal medulla from UUO-V group and l UUO-BBG group. All pictures of the sham control groups are shown in the supplementary material. Bar = 100 μm in all figures