Table 2.
Clinicopathological features of cN0 esophageal cancer patients
| All patients (n = 213) | Lymph node involvement | p | |
|---|---|---|---|
| Positive (n = 60) | Negative (n = 153) | ||
| Gender | 0.712 | ||
| Female | 9 | 20 | |
| Male | 51 | 133 | |
| Age at surgery | 67 (51–85) | 66 (39–81) | 0.890 |
| Tumor location | 0.338 | ||
| Upper | 4 | 18 | |
| Middle | 33 | 79 | |
| Lower | 23 | 56 | |
| Tumor size (mm) | 40 (10–95) | 35 (10–106) | 0.146 |
| Tumor depth (pT) | < 0.0001* | ||
| T1 | 29 | 123 | |
| T2 | 7 | 10 | |
| T3 | 22 | 18 | |
| T4a | 2 | 0 | |
| T4b | 0 | 2 | |
| Lymph node metastasis (pN) | < 0.0001* | ||
| N0 | 0 | 152 | |
| N1 | 45 | 0 | |
| N2 | 12 | 1 | |
| N3 | 3 | 0 | |
| Pathological stage | < 0.0001* | ||
| IA | 1 | 109 | |
| IB | 0 | 23 | |
| IIA | 0 | 18 | |
| IIB | 27 | 0 | |
| IIIA | 23 | 1 | |
| IIIB | 4 | 0 | |
| IIIC | 5 | 2 | |
| Tumor histology | 0.032* | ||
| Squamous cell carcinoma | 49 | 141 | |
| Adenocarcinoma | 5 | 6 | |
| Other | 6 | 6 | |
| Tumor differentiation of SCC | |||
| G1 | 11 | 17 | 0.005* |
| G2 | 23 | 101 | |
| G3 | 15 | 21 | |
| N/A | 0 | 2 | |
| Prognosis | |||
| Alive | 40 | 124 | 0.017* |
| Deceased from esophageal ca. | 10 | 7 | |
| Deceased from other ca. | 0 | 4 | |
| Deceased from other diseases | 10 | 18 | |
*Statistically significant