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Oxylipin analysis of blood and brain regions. (A) Arachidonic acid is metabolized to 8,9-EpETrE by several cytochrome P450 enzymes. Subsequently, 8,9-EpETrE is metabolized to 8,9-DiHETrE by sEH. (B) Levels of 8,9-EpETrE in the plasma, PFC, hippocampus, and striatum from juvenile offspring (P28). The values represent the mean ± SEM (n = 8 to 10; *P < 0.05, **P < 0.01 compared to control group by Student t test).
