Table 4:
Results of the analysis of the HIV-surveillance data: fitting a two-phase piecewise linear model (with an unknown change-point) to the jurisdiction-specific L2C measures in the HPTN 065 study based on the proposed estimator solving (5).
| City jurisdiction |
|||||||
|---|---|---|---|---|---|---|---|
| DC | Miami | Chicago | New york | Philadelphia | Houston | ||
| Estimation of the change-point model parameters | |||||||
| β0 | Estimate | 71.25 | 42.21 | 74.13 | 78.60 | 74.19 | 49.43 |
| SE | 0.76 | 0.70 | 1.15 | 1.22 | 0.06 | 0.86 | |
| 95% CI | (69.76, 72.74) | (40.84, 43.59) | (71.88, 76.38) | (76.21, 81.00) | (74.07, 74.31) | (47.74, 51.12) | |
| β1 | Estimate | 3.29 | 3.13 | 0.96 | 3.58 | 2.92 | 16.37 |
| SE | 0.61 | 0.39 | 0.27 | 0.67 | 0.05 | 1.26 | |
| 95% CI | (2.09, 4.48) | (2.37, 3.90) | (0.44, 1.49) | (2.26, 4.90) | (2.82, 3.02) | (13.90, 18.83) | |
| β2 | Estimate | −3.01 | −2.93 | −0.96 | −3.87 | −3.0 | −16.04 |
| SE | 0.61 | 0.39 | 0.77 | 0.69 | 0.05 | 1.26 | |
| 95% CI | (−4.21, −1.80) | (−3.70, −2.16) | (−2.47, 0.55) | (−5.22, −2.52) | (−3.10, −2.90) | (−18.50, −13.57) | |
| τ | Estimate | 2.96 | 3.35 | 7.52 | 3.38 | 2.34 | 1.55 |
| SE | 0.46 | 0.39 | 1.96 | 0.47 | 0.03 | 0.10 | |
| 95% CI | (2.05, 3.87) | (2.66, 4.04) | (3.67, 11.36) | (2.46, 4.31) | (2.28, 2.40) | (1.36, 1.74) | |
| Annual percentage of linkage to care | |||||||
| % | Estimate | 82.13 | 53.54 | 81.44 | 89.68 | 80.62 | 76.42 |
Note: β0 is the intercept; β1 is the slope of the first segment; β2 is the difference in slopes between the two segments; τ is the jurisdiction change-point.