Table 1.
Demographic characteristics of included studies
| Study | Date of publication in mm-yy | Country of study | Number of patients with confirmed COVID-19 on RT-CR | Males | Females | Age (in years) (mean or median) | Age range/IQR |
|---|---|---|---|---|---|---|---|
| Huang et al [8] | Jan-20 | China | 41 | 30 | 11 | 49 | IQR = 41–58 |
| Xie et al [9] | Feb-20 | China | 167 | NP | NP | NP | NP |
| Song et al [10] | Feb-20 | China | 51 | 25 | 26 | 49 ± 16 | 16–76 |
| Chung et al [11] | Feb-20 | China | 21 | 13 | 8 | 51 ± 14 | 29–77 |
| Wang et al [12] | Feb-20 | China | 138 | 75 | 63 | Median = 56 (IQR, 42–68) | 22–92 |
| Chen et al [13] | Jan-20 | China | 99 | 67 | 32 | 55.5 ± 13.1 | Not provided |
| Chan et al [14] | Feb-20 | China | 5 | 3 | 3 | 48.6 | 10–66 (1 patient was 10 years old) |
| Chang et al [15] | Feb-20 | China | 9 | 10 | 3 | Median = 34 | IQR = 34–48 |
| Pan et al [16] | Feb-20 | China | 63 | 33 | 30 | 44.9 ± 15.2 | 25–63 |
| Pan et al [17] | Feb-20 | China | 21 | 6 | 15 | 40 | 25–63 |
| Diao et al [18] | Feb-20 | China | 6 | 3 | 3 | 47.5 | 19–59 |
| Chen et al [19] | Feb-20 | China | 9 | 0 | 9 | NP | 26–40 |
| Ng et al [20] | Feb-20 | China | 21 | 13 | 8 | Median = 56 | IQR = 37–65 |
| Wang et al [3] | Mar-20 | China | 90 | 33 | 57 | 45 | |
| Inui et al [21] | Mar-20 | Japan | 104 | 54 | 50 | 62 ± 16 | 31–87 |
| Lei et al [22] | Mar-20 | China | 49 | 27 | 22 | 41 | 25–70 |
| Zhu et al [23] | Mar-20 | China | 6 | 0 | 6 | 44 | 27–63 |
| Xu et al [24] | Mar-20 | China | 50 | 29 | 21 | 43.9 ± 16.8 | 3–85 (five (10%) patients were below the age of 18 years) |
| Bernheim et al [25] | Feb-20 | China | 121 | 61 | 60 | 45 ± 15.6 | 18–80 |
| Wu et al [26] | Mar-20 | China | 80 | 42 | 38 | 44 ± 11 | 15–79 |
| Li and Xia [27] | Feb-20 | China | 51 | 28 | 23 | 58 | 26–83 |
| Zhou et al [28] | Feb-20 | China | 62 | 39 | 23 | 52.8 ± 12.2 | 30–77 |
| Cheng et al [29] | Mar-20 | China | 11 | 8 | 3 | 50.3 ± 15.5 | Not provided |
| Shi et al [30] | Feb-20 | China | 81 | 42 | 39 | 49.5 ± 11 | 25–81 |
| Xu et al [31] | Feb-20 | China | 90 | 39 | 51 | 50 | 18–86 |
| Liu et al [32] | Mar-20 | China | 73 | 41 | 32 | 41.6 ± 14.5 | Not provided |
| Zhao et al [33] | Feb-20 | China | 101 | 56 | 45 | 44.44 | 21–50 |
| Guan et al [34] | Mar-20 | China | 53 | NP | NP | NP | NP |
| Zhou et al [35] | Mar-20 | China | 62 | 34 | 28 | 47.5 ± 13 | 20–91 |
| Li et al [36] | Apr-20 | China | 131 | 63 | 68 | 47 ± 15 | 20–90 |
| Wang et al [37] | Apr-20 | China | 1012 | NP | NP | Median = 50 | IQR = 39–58 |
| Gao et al [38] | Mar-20 | China | 6 | 1 | 5 | 40 ± 10 | Not provided |
| Caruso et al [39] | Apr-20 | Italy | 62 | NP | NP | 57 | 18–89 |
| Iwasawa et al [40] | Mar-20 | Japan | 6 | 2 | 4 | 57.16 | 63–71 |
| Zhu et al [41] | Mar-20 | China | 72 | 42 | 30 | 55.6 ± 12.8 | 30–83 |
| Himoto et al [42] | Mar-20 | Japan | 6 | 5 | 1 | 58.5 | 45–81 |
| Long et al [43] | Mar-20 | China | 36 | 20 | 16 | 44.8 ± 18.2 | Not provided |
| Han et al [44] | Mar-20 | China | 17 | 6 | 11 | 40 ± 10 | 27–60 |
| Zhang et al [45] | Mar-20 | China | 28 | 17 | 11 | Median = 65 | IQR = 56.0–70.0 |
| Chen et al [46] | Mar-20 | China | 5 | 0 | 5 | 28.8 | 25–31 |
| Yang et al [47] | Mar-20 | China | 44 | 25 | 19 | Median = 48.5 | 20–76 |
| Wang et al [48] | Mar-20 | China | 114 | 56 | 58 | Median = 53 | 23–78 |
| Ai et al [49] | Feb-20 | China | 1014 (601 positive on RT-PCR) | 467(46%) | 51 ± 15 | 2 to 95 | |
| Yoon et al [50] | Mar-20 | S. Korea | 9 | 4 | 5 | Median = 54 | Not provided |
| Fang et al [51] | Feb-20 | China | 51 | 29 | 22 | Median = 45 | IQR = 39–55 |
IQR, interquartile range; NP, not provided