Scheme 2.
Cyclic and noncyclic glutamate analogues such as (2S, 4R)-4-methyl-glutamate (IC 50 = 0.7 mM), DL-trans-ACHD (IC50 = 0.8 mM) or L-trans-ACPD (IC 50 = 0.23 mM) (Thompson et al., 2005)
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