Table 2.
Daptomycin MICs and MBCs for VREfm isolates with mutations in lipid metabolism genes
| Isolate | ST | Source | Genotype | Daptomycin MIC (µg/mL) | Daptomycin MBC (µg/mL) |
| 13-10-S | 412 | GI | Wild type | 2 | 16 |
| 13-14-B | 412 | Blood | dagK(P226A) | 1 | 2 |
| 15-10-S | 412 | GI | Wild type | 2 | 16 |
| 15-12-B | 412 | Blood | dgkA (G106E) | 1 | 2 |
| 28-10-S | 736 | GI | Wild type | 4 | 8 to 16 |
| 28-14-B | 736 | Blood | dgkA (indel) | 4 | 8 to 16 |
| 28-16-S | 736 | GI | clsA (A20D) | 8 | 32 |
| 28-17-B | 736 | Blood | clsA (A20D) | 8 | 32 to 64 |
| 31-13-S | 203 | GI | Wild type | 4 | 8 to 16 |
| 31-36-S | 203 | GI | clsA (D27N) | 8 | 32 |
| 31-38-S | 203 | GI | clsA (D27N) | 8 | 32 |
| 31-39-B | 203 | Blood | clsA (D27N) | 8 | 16 |
GI, gastrointestinal.