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. 2020 Apr 24;48(10):5254–5267. doi: 10.1093/nar/gkaa281

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — The competitive effect of GQ-binding ligands. (A) A schematic showing of 10 min treatments of ∼1 μM heme–GQ complex (made by complexation of 1 μM ‘CatG4-ext’ with 5 μM hemin) with 20 μM of, individually, NMM, pyridostatin and BRACO19 GQ-binding ligands. (B) A native gel showing StAv-retarded bands of biotinylated CatG4-ext complexed with added StAv (shown with a red arrow). The percentage of this retarded complex (with respect to the total DNA in a given lane) is indicated in blue above each lane.