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. 2020 Apr 30;48(10):5639–5655. doi: 10.1093/nar/gkaa284

Figure 3.

Figure 3.

Cohesin SA1 and SA2 bind to long ssRNA transcripts. (A) A representative AFM image of RNA transcripts after purification using the MEGAclear Transcription Clean-up kit. (B and C) AFM images of RNA transcripts in the presence of SA1 (B) or SA2 (C). (D) Histograms of the maximum AFM height (left panel) and AFM volume (right panel) for RNA transcripts alone (black bars, N = 255), and for RNA transcripts in the presence of either SA1 (red bars, N = 135) or SA2 (blue bars, N = 135). Each data set was from two to three independent experiments.