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. 2020 Apr 30;48(10):5639–5655. doi: 10.1093/nar/gkaa284

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© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 9. — R-loop-localized SA1 and SA2 are enriched for positions near the TSS and typically in the cohesin complex. (A) The distance to nearest TSS for SA1, SA2, SA1 + SA2 (common), SA1/SA2 overlapping with R-loops (SA1 + SA2 ol w/DRIP), or without overlapping with DRIP-peaks (SA1 + SA2 no ol w/DRIP). **** P ≤ 0.0001 based on Wilcoxon rank sum test. (B) Venn diagrams showing the overlap of the R-loop-localized SA1/SA2 (e.g. SA1_ol_DRIP and SA2_ol_DRIP) with the SMC subunit (SMC1 or SMC3) and CTCF sites.