Table 2.
Group differences in rsFC for ACC and amygdala seed ROIs
| Seed ROI | Cluster location | MNI coordinates (x, y, z) |
Cluster size (voxels) |
t-value | Average connectivity AHI a, b (n = 74) |
Average connectivity CO a, b (n = 30) |
|---|---|---|---|---|---|---|
| pgACC | n/a | -- | -- | -- | -- | -- |
| Anterior sgACC | n/a | -- | -- | -- | -- | -- |
| Posterior sgACC | n/a | -- | -- | -- | -- | -- |
| L amygdala | right parahippocampal gyrus | 15, −12, −22 | 244 | 4.76 | 7.18 | −1.06 |
| R amygdala | right cerebellum | 21, −36, −28 | 713 | 4.83 | −0.52 | −4.88 |
| left cerebellar tonsil | −17, −40, −34 | 187 | 4.37 | −2.40 | −5.04 |
Notes. AHI = Acute HIV, CO = HIV-negative control group; pgACC = pregenual anterior cingulate cortex, sgACC = subgenual anterior cingulate cortex. (pFWE = .01, Bonferroni-corrected for number of seeds, p = .05/5 = .01; uncorrected p = .001).
a
LPI coordinate order
b
Average connectivity of seed ROI to cluster location (t-values), without any covariates. There were no significant group differences in rsFC of ACC seed ROIs (each pFWE > .01).