Table 3.
Multivariable analysis for post-treatment wish for parenthood and univariable analysis for fulfillment of desired parenthood
| Wish for post-treatment parenthood | Fulfillment of parenthood | |||
|---|---|---|---|---|
| Odds ratio | 95% CI | Odds ratio | 95% CI | |
| Female sex | 0.69 | 0.45–1.05 | 0.82 | 0.42–1.62 |
| Agea | 0.60 | 0.52–0.69 | 0.92 | 0.72–1.18 |
| Calendar year of diagnosisa | 1.97 | 0.16–23.60 | 0.75 | 0.60–0.95 |
| Time interval since last treatmenta | 2.12 | 0.18–25.66 | 1.34 | 1.06–1.69 |
| Use of fertility preservation | 2.84 | 1.75–4.61 | 1.12 | 0.58–2.16 |
| ≥ 1 child at time of diagnosis | 0.54 | 0.33–0.88 | 3.1 | 1.54–6.22 |
| Disease | ||||
| Acute leukemia (reference) | 1.0 | n.a | 1.0 | n.a |
| Multiple myeloma | 0.34 | 0.03–3.95 | – | – |
| Indolent non-Hodgkin lymphoma | 0.61 | 0.22–1.70 | 5.13 | 1.06–24.87 |
| Myeloproliferative neoplasm | 0.87 | 0.48–1.58 | 0.62 | 0.17–2.25 |
| Aggressive non-Hodgkin or Hodgkin’s lymphoma | 0.83 | 0.40–1.72 | 4.39 | 1.83–10.58 |
| Therapy | ||||
| Chemotherapy/exclusive (reference) | 1.0 | n.a | 1.0 | n.a |
| Chemotherapy/combined | 1.38 | 0.86–2.22 | 0.81 | 0.35–1.89 |
| Autologous stem cell transplantation | 1.53 | 0.77–3.05 | 1.52 | 0.56–4.17 |
| Allogeneic stem cell transplantation | 0.86 | 0.45–1.63 | 0.18 | 0.08–0.41 |
| Other | 1.07 | 0.59–1.93 | 0.84 | 0.32–2.20 |
CI confidence interval, n.a. not applicable
aPer 5 years