Table 1.

Hypoglycaemia risk comparison of participants with T2DM treated with Gla-300 versus Gla-100

Risk index	EDITION 2			EDITION 3			SENIOR
	Gla-300	Gla-100	p value	Gla-300	Gla-100	p value	Gla-300	Gla-100	p value
LBGI
Titration	0.33	0.51	< 0.0001	0.24	0.30	0.0587	0.28	0.34	0.1167
Maintenance	0.41	0.50	0.043	0.38	0.41	0.4205	0.34	0.44	0.0125
Overall p value			0.0003			0.1012			0.0084
Nocturnal LBGI
Titration	0.72	1.29	< 0.0001	0.50	0.59	0.1838	0.39	0.51	0.0604
Maintenance	0.98	1.24	0.0387	0.73	0.92	0.0176	0.52	0.67	0.0270
Overall p value			< 0.0001			0.0167			0.0082

The data points represent mean values unless otherwise indicated

Gla-100 insulin glargine 100 U/mL, Gla-300 insulin glargine 300 U/mL, LBGI low blood glucose index

p value represents treatment differences between Gla-300 and Gla-100 within the titration, maintenance or overall (titration and maintenance) trial periods