. 2020 Apr 22;11(Suppl 1):15–22. doi: 10.1007/s13300-020-00812-2

Table 2.

Risk of hypoglycaemia in the CAROLINA study [18]

	Rates of hypoglycaemia, %		HR (95% CI)	p value
	Linagliptin	Glimepiride	HR (95% CI)	p value
Any	10.6	37.7	0.23 (0.21, 0.26)	< 0.001
Moderate or severe	6.5	30.9	0.18 (0.15, 0.21)	< 0.001
Severe^a	0.3	2.2	0.15 (0.08, 0.29)	< 0.001
Hospitalisation due to hypoglycaemia	0.1	0.9	0.07 (0.02, 0.31)	< 0.001

CI confidence interval, HR hazard ratio

^aHypoglycaemic event requiring the assistance of another person to actively administer carbohydrate, glucagon or other resuscitative actions