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. 2020 May 22;2020:8249497. doi: 10.1155/2020/8249497

Table 1.

Baseline characteristics of patients based on the severity of PVL.

Clinical characteristics All (n = 256) ≥mild PVL (n = 75) <mild PVL (n = 181) p value
Age (year) 74 ± 6 73.68 ± 5.89 74.17 ± 6.19 0.56
Female gender 111 (43.4%) 29 (38.7%) 82 (45.3%) 0.33
Body mass index 22.12 ± 3.44 21.88 ± 3.30 22.35 ± 3.59 0.33
STS SCORE 8.01 ± 4.4 8.1 ± 4.01 7.93 ± 4.78 0.80
History of dyspnoea 230 (89.8%) 65 (86.7%) 165 (91.2%) 0.27
History of chest pain 74 (28.9%) 19 (25.3%) 55 (30.4%) 0.42
History of syncope 41 (16.4%) 13 (17.3%) 28 (15.5%) 0.71
Hypertension 114 (44.5%) 37 (49.3%) 77 (42.5%) 0.32
Diabetes mellitus 46 (17.9%) 15 (20%) 31 (17.1%) 0.59
Chronic obstructive pulmonary disease 162 (63.2%) 50 (66.7%) 112 (61.9%) 0.47
Coronary artery disease 110 (42.9%) 32 (42.7%) 78 (43.1%) 0.95
Previous myocardial infarction 5 (1.9%) 2 (2.7%) 3 (1.7%) 0.61
Peripheral vascular disease 143 (55.8%) 35 (46.7%) 108 (59.7%) 0.057
Prior stroke or transient ischemic attack 34 (13.2%) 8 (10.7%) 26 (14.4%) 0.43
Chronic kidney disease 36 (14.0%) 13 (17.3%) 23 (12.7%) 0.33
Atrial fibrillation 37 (14.4%) 9 (12%) 28 (15.5%) 0.47
NYHA 0.88
 Class I 1 (0.4%) 0 1 (1.6%)
 Class II 21 (8.2%) 6 (8%) 15 (8.3%)
 Class III 113 (44.1%) 35 (46.7%) 78 (43.1%)
 Class IV 121 (47.2%) 34 (45.3%) 87 (48.1%)
 NYHA III/IV 234 (91.4%) 69 (92%) 165 (91.2%) 0.82
Echocardiographic factors
 Left ventricular ejection fraction (%) 54.7 ± 15 52.93 ± 14.98 56.48 ± 15.12 0.088
 Aortic valve peak velocity (m/s) 5 ± 0.73 5.15 ± 0.75 4.94 ± 0.71 0.035
 Aortic valve mean pressure gradient (mm Hg) 64.32 ± 19.3 66.56 ± 20.57 62.08 ± 17.97 0.084
 Aortic regurgitation (moderate to severe) 60 (23.4%) 24 (26.3%) 36 (19.9%) 0.19
 Mitral regurgitation (moderate to severe) 43 (16.8%) 17 (19.5%) 26 (16%) 0.42

Data are presented as mean ± SD or percentages. NYHA: New York Heart Association; STS score: Society of Thoracic Surgeon score.