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. 2020 May 22;2020:8387654. doi: 10.1155/2020/8387654

Figure 3.

Figure 3

NOX expression in HUVECs induced by HUA or Ang II. (a, b) NOX2 and NOX4 protein expressions were assayed by Western blot. The HUA, Ang II, and HUA+Ang II groups showed increased NOX4 protein expression levels in HUVECs after 24 h of stimulation; p < 0.05 compared to the normal control group, but there is no difference of NOX2 expression between each group. The NOX4 protein expression level in the HUA+Ang II group was significantly higher than that in the HUA group or the Ang II group; #p < 0.05 compared to the Ang II group; p < 0.05 compared to the HUA group. (c) Also, NOX activity in HUA, Ang II, and HUA+Ang II groups increased remarkably when compared with normal control. Particularly, that was significantly higher in the HUA+Ang II group compared to that in the HUA or Ang II group; #p < 0.05 compared to the Ang II group; p < 0.05 compared to the HUA group.