Table 3.
Inhibition of activated factor XII (a-FXIIa) by five compounds.
| Compounds | Z1225120358 | Z432246974 | Z45287215 | Z30974175 | Z146790068 |
|---|---|---|---|---|---|
| pIC50 values (M) | 9.3∗10−7 | 3.0∗10−5 | 7.8∗10−7 | 8.7∗10−7 | 1.3∗10−6 |
Inhibition of activated factor XII (a-FXIIa) by five compounds.
| Compounds | Z1225120358 | Z432246974 | Z45287215 | Z30974175 | Z146790068 |
|---|---|---|---|---|---|
| pIC50 values (M) | 9.3∗10−7 | 3.0∗10−5 | 7.8∗10−7 | 8.7∗10−7 | 1.3∗10−6 |