TABLE 1.
Prevalence of laterality defects among different types of congenital heart defectsa
| HLHS (%) |
SV (%) |
TA (%) |
PTA (%) |
PA (%) |
TGA (%) |
DORV (%) |
AVSD/ ECD (%) | TAPVR (%) |
TOF (%) |
EB (%) |
Total (%) |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A. CHD associated with heterotaxy and situs inversus in national birth defects prevention study by Lin et al. (2014) | ||||||||||||
| Situs inversus | 1.4 | 5.8 | 0.7 | 0 | 1.4 | 2.4 | 7.9 | 5.0 | 2.2 | 2.9 | 0.7 | 43.2 |
| Heterotaxy | 3.2 | 14.0 | 2.1 | 1.1 | 9.8 | 3.7 | 25.7 | 48.4 | 31.2 | 4.2 | 0.3 | 96.6 |
| All laterality | 2.7 | 11.8 | 1.7 | 0.8 | 4.9 | 3.1 | 20.9 | 36.8 | 23.4 | 3.9 | 0.4 | 82.2 |
| B. Situs-related anomalies associated with CHD in birth defects registry study focused on congenital malformations by Pradat et al.(2003) | ||||||||||||
| Situs inversus | 4.7 | 17.6 | 0 | 1.0 | 9.8 | 5.7 | 13.6 | 9.4 | 4.8 | 3.7 | 5.0 | 5.6 |
| Gut malrotation | 6.5 | 11.8 | 0 | 7.1 | 4.9 | 2.4 | 11.9 | 10.4 | 6.3 | 4.9 | 0 | 6.2 |
| Spleen abnormal | 7.7 | 23.5 | 4.1 | 6.1 | 4.9 | 4.9 | 8.5 | 11.3 | 12.7 | 5.8 | 0 | 7.5 |
a
HLHS, hypoplastic left heart syndrome; SV, single ventricle; TA, tricuspid atresia; PTA, persistent truncus arteriosus; PA, pulmonary atresia; TGA, transposition of the great arteries; DORV, double outlet right ventricle; AVSD/ECD, atrioventricular septal defect/endocardial cushion defect; TAPVR, total anomalous pulmonary venous return; TOF, tetralogy of Fallot; EB, Ebstein’s anomaly.