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. 2020 May 30;19:71. doi: 10.1186/s12933-020-01045-0

Table 3.

Independent predictors for ruptured culprit plaque

Model 1 Univariate Multivariate Model 2 Univariate Multivariate
OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value
Age 0.992 (0.958, 1.028) 0.672 Age (≥ 65 years) 0.869 (0.414, 1.824) 0.710
Female 1.305 (0.608, 2.801) 0.494 Female 1.305 (0.608, 2.801) 0.494
Current smoking 2.278 (0.961, 5.398) 0.062 2.647 (1.018, 6.883) 0.046 Current smoking 2.278 (0.961, 5.398) 0.062 3.529 (1.292, 9.638) 0.014
Duration of diabetes 1.059 (0.991, 1.130) 0.090 Duration of diabetes (Upper tertile, ≥ 4.8 years) 1.773 (0.851, 3.695) 0.126
Body mass index 1.102 (0.978, 1.243) 0.111 Body mass index (> 30 kg/m2) 1.956 (0.943, 4.055) 0.071
LVEF 0.968 (0.932, 1.006) 0.095 LVEF (< 40%) 1.718 (0.659, 4.479) 0.268
TG 1.353 (0.961, 1.906) 0.084 TG (> 1.70 mmol/L) 1.681 (0.810, 3.490) 0.164
Non-HDL-C 1.904 (1.233, 2.940) 0.004 1.983 (1.236, 3.183) 0.005 non-HDL-C (≥ 4.1 mmol/L) 4.016 (1.736, 9.293) 0.001 4.857 (1.871, 12.61) 0.001
hs-CRP 1.007 (0.940, 1.080) 0.837 hs-CRP (> 3 mg/L) 1.372 (0.668, 2.817) 0.389
1,5-AG 0.914 (0.856, 0.976) 0.007 0.916 (0.852, 0.985) 0.018 1, 5-AG (Lower tertile, < 9.78 µg/mL) 3.631 (1.752, 7.524) 0.001 3.421 (1.446, 8.092) 0.005
FBG 1.176 (1.019, 1.357) 0.026 FBG (≥ 7.0 mmol/L) 1.367 (0.685, 2.729) 0.375
HbA1c 1.989 (1.083, 3.653) 0.027 HbA1c (> 7%) 1.996 (0.984, 4.048) 0.055 2.458 (1.081, 5.586) 0.032
Urinary 8-iso-PGF 1.005 (1.000, 1.010) 0.042 Urinary 8-iso-PGF (Upper tertile, > 140 pmol/mmolCr) 2.493 (1.222, 5.085) 0.012

Model 1: Age, duration of diabetes, body mass index, LVEF, TG, non-HDL-C, hs-CRP, 1,5-AG, FBG, HbA1c and urinary 8-iso-PGF were included as continuous variables. Model 2: All variables were included as categorized variables

LVEF left ventricular ejection fraction, TG triglycerides, non-HDL-C non-high-density lipoprotein cholesterol, hs-CRP high-sensitivity C-reactive protein, 1,5-AG 1,5-anhydroglucitol, FBG fasting blood glucose, HbA1c hemoglobin A1c, 8-iso-PGF 8-iso-prostaglandin F