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Effects of inhibitors on target cells
| Inhibitor | LC50a,b (μM) | TId |
|---|---|---|
| 9a | 200 | <10 |
| 9e | Non-toxicc | >30–60 |
| 11a | Non-toxic | >30–60 |
| 11d | 200 | 10–60 |
| 11e | 370 | 13–150 |
| 11g | Non-toxic | 16–170 |
| 11i | 70 | <10 |
| 11j | 330 | 13–300 |
Effects on host cell line (TZM-bl).
Standard deviations averaged 15%.
Non-toxic at 500 μM.
Range takes into account differing potencies toward various strains.
