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Temporal changes of cell-mediated immune responses in 11 patients with COVID-19 according to severity. Frequencies of Ki-67+, PD-1+, perforin+, granzyme B+ CD8+ T cells, and IL-7Rαlow effector memory CD8+ T cells in severe (n = 3) or mild (n = 8) cases from the first week (closed circle) to the third week (open circle).
