Table 1.
Clinical and laboratory characteristics of patients in mild and severe groups.
| Mild (n = 8) | Severe (n = 4) | P | |
|---|---|---|---|
| Male, n (%) | 2 (25.0) | 2 (50.0) | 0.547 |
| Age, median years (range) | 55 (25–79) | 62 (35–82) | 0.552 |
| White blood cells, cells/mm3, median (range) | |||
| At week 1 | 4125 (2780–6500) | 5210 (3160–8760) | 0.540 |
| At week 3 | 5080 (4220–7750) | 7535 (3900–14,180) | 0.396 |
| Hemoglobin, g/dL, median (range) | |||
| At week 1 | 13.5 (11.0–16.0) | 12.0 (11.0–13.1) | 0.179 |
| At week 3 | 12.0 (11.5–15.0) | 11.7 (9.0–13.0) | 0.218 |
| Platelets, 1000 cells/mm3, median (range) | |||
| At week 1 | 192 (159–396) | 263 (166–316) | 0.307 |
| At week 3 | 237 (185–386) | 317 (210–459) | 0.234 |
| C-reactive protein, mg/dL, median (range) | |||
| At week 1 | 0.7 (0.0–6.6) | 1.6 (1.6–14.9) | 0.041 |
| At week 3 | 0.1 (0.0–0.7) | 7.6 (4.5–28.5) | 0.006 |
| LDH, U/L, median (range) | |||
| At week 1 | 162 (131–350) | 439 (223–455) | 0.053 |
| At week 3 | 163 (129–411) | 393 (254–561) | 0.023 |
| Ct for E gene from NP swabs, median (range) | |||
| At week 1 | 24.78 (17.3–40.0) | 29.3 (26.8–32.1) | 0.221 |
| At week 3 | 39.3 (29.1–40.0) | 35.4 (29.7–40.0) | 0.725 |
| Oxygen therapy | – | ||
| Start date, day of illness, median (range) | – | 9 (4–14) | – |
| At week 3, median (range) | – | 6 L/min (4 L/min to MV) | – |
| Peak oxygen demand, median (range) | – | 6 L/min (6 L/min to MV) | – |
LDH, lactate dehydrogenase; Ct, cycle threshold; E gene, SARS-CoV-2 envelope gene; NP, nasopharyngeal; MV, mechanical ventilation.