Table 2.
Distribution of urinary organophosphate flame retardant metabolites (ug/L) measured among 155 women with 339 cycle-specific urine samples in the EARTH Study.
Specific Gravity Adjusteda | N > MDLb (%) | GM (95% CI) | Min | 10th Pctl | 25th Pctl | 50th Pctl | 75th Pctl | 90th Pctl | 95th Pctl | Max |
---|---|---|---|---|---|---|---|---|---|---|
BCIPP | 0 (0) | N/A | <MDL | <MDL | <MDL | <MDL | <MDL | <MDL | <MDL | <MDL |
BDCIPP | 329 (94) | 0.69 (0.59, 0.80) | <MDL | 0.19 | 0.30 | 0.65 | 1.46 | 2.72 | 4.03 | 6.74 |
DPHP | 335 (98) | 0.80 (0.69, 0.92) | <MDL | 0.30 | 0.47 | 0.73 | 1.19 | 2.34 | 3.52 | 657 |
ip-PPP | 315 (87) | 0.09 (0.07, 0.11) | <MDL | 0.02 | 0.05 | 0.24 | 0.39 | 0.32 | 0.55 | 76.1 |
tb-DPP | 201 (23) | N/A | <MDL | <MDL | 0.06 | 0.08 | 0.20 | 0.36 | 374 | 374 |
ΣPFRc | - | 7.89 (7.12, 8.73) | 1.5 | 3.7 | 4.54 | 7.25 | 1.16 | 1.96 | 2.55 | 2.89 |
Adjusted to specific gravity, range (1.002–1.028).
Abbreviations: < MDL, method detection limit; Max, maximum; Pctl: percentile; Min, minimum; [bis(1,3-dichloro-2-propyl) phosphate (BDCIPP); diphenyl phosphate (DPHP); isopropylphenyl phenyl phosphate (ip-PPP); tert-butylphenyl phenyl phosphate (tb-PPP); bis(1-chloro-2-propyl) phosphate (BCIPP)].
All values below MDL were assigned a value equal to the MDL divided by √2.
ΣPFR is the molar sum of the three organophosphate flame retardant metabolite concentrations with high detection frequencies: (BDCIPP*(1/319.91) + (DPHP*(1/250.04) + ipPPP*(1/292.09). Concentrations shown in mol/ml X10–9.