Table 1.
Baseline characteristics and biochemical parameters of the study groups
| Parameter |
Controls N = 20 |
All patients N = 35 |
P‐value |
RHI > 1.81 N = 17 |
RHI ≤ 1.81 N = 18 |
P‐value |
|---|---|---|---|---|---|---|
| Age, mean ± SD (years) | 48 ± 14 | 42 ± 11 | 0.9 | 43 ± 14 | 41 ± 9 | 0.8 |
| Female sex, N (%) | 10 (50) | 24 (69) | 0.2 | 13 (77) | 11 (61) | 0.3 |
| Body mass index, mean ± SD (kg/m2) | 24.4 ± 3.3 | 23.8 ± 4.2 | 0.6 | 24.4 ± 4.2 | 23.2 ± 4.3 | 0.4 |
| Heart rate, mean ± SD (b.p.m.) | 61 ± 8 | 68 ± 13 | 0.03 | 68 ± 15 | 68 ± 10 | 0.9 |
| Systolic blood pressure, mean ± SD (mmHg) | 123 ± 14 | 126 ± 15 | 0.5 | 128 ± 19 | 124 ± 11 | 0.4 |
| Diastolic blood pressure, mean ± SD (mmHg) | 74 ± 8 | 79 ± 12 | 0.1 | 79 ± 14 | 79 ± 9 | 1.0 |
| Biochemical parameters | ||||||
| C‐reactive protein, mean ± SD (mg/dL) | 1.5 (0.7–2.2) | 0.6 (0.3–1.2) | 0.9 | 0.6 (0.3–3.3) | 0.7 (0.3–1.1) | 1.0 |
| Albumin, mean ± SD (g/L) | 38.6 ± 3.1 | 45.2 ± 3.0 | <0.001 | 45.0 ± 3.3 | 45.3 ± 2.8 | 0.8 |
| Haemoglobin, mean ± SD (g/dL) | 13.6 ± 0.8 | 14.2 ± 1.3 | 0.2 | 14.2 ± 1.1 | 14.2 ± 1.4 | 1.0 |
| Creatinine, mean ± SD (mg/dL) | 0.9 ± 0.1 | 0.8 ± 0.1 | 0.01 | 0.8 ± 0.1 | 0.79 ± 0.11 | 0.8 |
| Aspartate transaminase, mean ± SD (U/L) | 26.6 ± 8.2 | 25.4 ± 7.3 | 0.5 | 25.4 ± 8.0 | 24.4 ± 6.9 | 1.0 |
| Alanine transaminase, mean ± SD (U/L) | 21.2 ± 10.9 | 26.7 ± 17.1 | 0.3 | 24.8 ± 19.7 | 28.4 ± 14.8 | 0.6 |
| Gamma‐glutamyltransferase, mean ± SD (U/L) | 23.9 ± 13.8 | 21.5 ± 21.1 | 0.3 | 23.5 ± 25.4 | 19.5 ± 15.0 | 0.6 |
| Haemoglobin A1c, median (IQR) [ln (%)] | 5.3 ± 0.4 | 5.4 ± 1.0 | 0.9 | 5.4 ± 0.6 | 5.4 ± 1.3 | 1.0 |
IQR, interquartile range; RHI, reactive hyperaemia index; SD, standard deviation.