Table 1.
A: Baseline characteristics of all patients with left ventricular assist device explantation due to myocardial recovery with and without follow‐up after explantation
| With follow‐up (28) | No follow‐up (17) | P‐value | |
|---|---|---|---|
| Age (years) | 43 (29–52) | 53 (41–65) | 0.053 |
| Male | 23 (82.1) | 13 (76.5) | 0.711 |
| BMI(kg/m2) | 26.9 [25.1–28.6] | 25.7 [23.2–28.2] | 0.182 |
| BSA(m2) | 2.02 [1.92–2.12] | 1.98 [1.87–2.10] | 0.395 |
| Aetiology | 0.579 | ||
| Myocarditis | 9 (32.1) | 3 (17.6) | |
| Dilated cardiomyopathy | 10 (35.7) | 4 (23.5) | |
| Ischaemic cardiomyopathy | 4 (14.3) | 5 (27.1) | |
| Peripartum | 1 (3.6) | 1 (5.9) | |
| Valvular heart disease | 2 (7.1) | 2 (11.8) | |
| Hypertrophic cardiomyopathy | 0 (0) | 1 (5.9) | |
| Toxic | 1 (3.6) | 0 (0) | |
| Restrictive cardiomyopathy | 0 (0) | 0 (0) | |
| Congenital heart disease | 0 (0) | 0 (0) | |
| Other/unknown | 1 (3.6) | 1 (5.9) | |
| Time since first cardiac diagnosis | 0.453 | ||
| <1 month | 14 (50) | 6 (35.3) | |
| 1 month–1 year | 6 (21.4) | 5 (29.4) | |
| 1 year or more | 4 (14.3) | 5 (29.4) | |
| Unknown | 4 (14.3) | 1 (5.9) | |
| Current ICD in place | 2 (7.1) | 2 (11.8) | 1.000 |
| INTERMACS profiles | 0.918 | ||
| INTERMACS 1 | 8 (28.6) | 6 (35.3) | |
| INTERMACS 2 | 9 (32.1) | 6 (35.3) | |
| INTERMACS 3 | 8 (28.6) | 3 (17.6) | |
| INTERMACS 4–5 | 3 (10.7) | 2 (11.8) | |
| INTERMACS 6–7 | 0 (0) | 0 (0) | |
| Echocardiography | |||
| LVEF (%) | 18 (10–20) | 15 (15–20) | 0.612 |
| LVEDD (mm) | 68 (63–70) | 66 (62–73) | 0.771 |
| Aortic regurgitation ≥ moderate | 1 | 0 | 1.000 |
| Mitral regurgitation ≥ moderate | 4 | 9 | 0.038 |
| ECG rhythm | 0.389 | ||
| Sinus | 18 (64.3) | 14 (82.4) | |
| Atrial fibrillation/flutter | 5 (17.9) | 3 (17.6) | |
| Paced | 1 (3.6) | 0 (0) | |
| Other/unknown | 4 (14.3) | 0 (0) | |
| Heart rate (b.p.m.) | 97 (89–121) | 98 (74–111) | 0.455 |
| Blood pressure (mmHg) | |||
| Systolic | 105 (92–115) | 106 (94–114) | 0.919 |
| Diastolic | 61 (60–70) | 67 (50–70) | 0.942 |
| Mean arterial pressure | 74 (72–84) | 78 (70–82) | 0.965 |
| Diabetes | 2 (7.1) | 0 (0) | 0.519 |
| Inotropic support | |||
| Intravenous inotropes | 23 (82.1) | 14 (82.4) | 0.333 |
| 1–2 inotropes | 18 (64.3) | 8 (47.1) | |
| ≥3 inotropes | 5 (17.9) | 6 (35.3) | |
| IABP | 4 (14.3) | 3 (17.6) | 1.000 |
| ECLS | 10 (35.7) | 7 (41.2) | 0.715 |
| Mechanical ventilation | 8 (28.6) | 6 (35.3) | 0.637 |
| Blood chemistry | |||
| Creatinine (μmol/L) | 105 (79–114) | 114 (91–141) | 0.142 |
| ALAT (U/L) | 76 (39–177) | 46 (34–520) | 0.892 |
| ASAT (U/L) | 180 (42–592) | 73 (27–184) | 0.147 |
| LDH (U/L) | 469 (308–1189) | 407 (338–992) | 0.859 |
| Total bilirubin (mg/dL) | 1.5 (0.8–2.5) | 1.5 (0.8–2.1) | 0.525 |
| Haemoglobin (g/dL) | 11.8 (10.2–13.4) | 10.9 (10.4–13.7) | 0.971 |
| White blood cell count (× 109/L) | 10.6 (9.3–14.3) | 10.7 (8.7–13.4) | 0.819 |
| Thrombocytes (× 109/L) | 164 (75–241) | 191 (104–266) | 0.479 |
ALAT, alanine aminotransaminase; ASAT, aspartate transaminase; BMI, body mass index; BSA, body surface area; ECG, electrocardiogram; ECLS, extracorporeal life support; IABP, intra‐aortic balloon pump; ICD, implantable cardioverter‐defibrillator; INTERMACS, Interagency Registry for Mechanically Assisted Circulatory Support; LDH, lactate dehydrogenase; LVEDD, left ventricular end‐diastolic diameter; LVEF, left ventricular ejection fraction.
Values are median (inter‐quartile range), mean [confidence interval], or n (%).