Table 2.
Generic Substitutions Rates for 1 Week in November 2013, Ordered by Generic Substitution Rate.
| Therapeutic Class | Generic Substitution Rate % (95% CI) | Therapeutic Class | Generic Substitution Rate % (95% CI) |
|---|---|---|---|
| Thyroid hormones | 64 (64 to 64) | Cardiac, antiarrhythmic agentsa | 97 (97 to 97) |
| Estrogens and combinations | 71 (71 to 72) | ARBs/ combinationsa | 98 (98 to 98) |
| Anticonvulsants, hydantoin | 72 (71 to 72) | Adrenal hormones and combinationsa | 98 (98 to 98) |
| Androgens and combinations | 74 (74 to 75) | Antipsychoticsa | 99 (98 to 99) |
| Immunosuppressants | 82 (82 to 82) | Antidepressantsa | 99 (98 to 99) |
| Parathyroid hormones (calcitonin, spray)a | 83 (82 to 84) | Antiplatelet Agentsa | 99 (99 to 99) |
| Ocular preparations for pressure lowering | 85 (84 to 85) | Vasodilating Agentsa | 99 (99 to 99) |
| Stimulant, amphetamine type | 90 (90 to 90) | Antimanic agentsa (lithium) | 99 (99 to 99) |
| Anticonvulsants, succinimidesa | 92 (92 to 93) | Sympathomimetic agentsa | 99 (99 to 99) |
| Anticoagulants (warfarin) | 95 (95 to 96) | Bladder muscle relaxantsa | 100 (99 to 100) |
| Anticonvulsants, miscellaneousa | 96 (96 to 96) | Antiemeticsa | 100 (99 to 100) |
| Vascular 5HTI AGONIST a | 96 (96 to 97) | Amebicidesa (puromycin) | 100 (99 to 100) |
| Anesthetics, local (lidocaine)a | 97 (95 to 98) | Antigouta | 100 (99 to 100) |
Abbreviations: ARBs, angiotensin receptor blocker, 5-hydroxytryptamine; CI confidence interval.
a
Some classes not selected for modeling due to very high GSR (>95%), low total usage, or very mixed product class.