Table 2.
Laboratory parameters of patients infected with SARS-CoV-2
| Normal range | Total (n = 310) | Nonhypertension (n = 197) | Hypertension (n = 113) | P value | |
|---|---|---|---|---|---|
| Laboratory indices | |||||
| WBC, ×109/L | 4.00–10.00 | 5.53 (4.06–8.36) | 3.30 (2.62–8.70) | 7.52 (4.66–9.04) | <0.001 |
| NC, ×109/L | 1.80–6.30 | 4.36 (2.76–6.80) | 2.58 (1.90–6.92) | 7.91 (3.41–7.98) | <0.001 |
| LC, ×109/L | 1.10–3.20 | 0.84 (0.58–1.21) | 0.56 (0.49–1.42) | 0.73 (0.49–0.90) | 0.366 |
| NLR | < 5.87 | 5.09 (2.65–10.06) | 4.96 (1.92–10.99) | 9.98 (3.61–17.60) | 0.001 |
| SaO2, % | >95.0 | 95.7 (91.0–98.0) | 95.7 (92.3–97.7) | 96.6 (88.6–97.3) | 0.036 |
| TB, μmol/L | 5.10–19.00 | 11.20 (8.50–15.50) | 12.10 (8.85–13.20) | 10.70 (10.25–14.60) | 0.162 |
| ALT, U/L | 0–40 | 27 (17–49) | 26 (11–34) | 57 (31–113) | 0.007 |
| AST, U/L | 0–40 | 33.0 (23.0–50.6) | 33.0 (32.5–40.5) | 52.0 (30.5–76.0) | 0.083 |
| Albumin, g/L | 34.0–54.0 | 33.9 (29.7–37.6) | 28.3 (27.6–34.1) | 31.1 (29.7–35.6) | 0.002 |
| Globulin, g/L | 20.0–35.0 | 31.0 (26.7–34.8) | 30.9 (26.0–37.4) | 29.6 (28.0–32.2) | 0.034 |
| LDH, U/L | 109–245 | 289 (206–421) | 295 (233–374) | 325 (245–409) | 0.120 |
| Creatinine, μmol/L | 50.00–120.00 | 69.50 (56.70–85.38) | 66.70 (52.05–86.95) | 72.30 (55.45–84.85) | 0.009 |
| ESR, mm/h | <15.0 | 46.7 (28.8–63.0) | 58.0 (21.5–61.0) | 43.0 (29.5–63.5) | 0.104 |
| CRP, mg/L | <8.0 | 14.7 (3.1–73.8) | 44.3 (20.8–112.2) | 35.3 (13.9–91.7) | 0.001 |
| Serum ferritin, ng/mL | 21.80–275.0 | 787.57 (398.74–1290.13) | 831.72 (503.48–1337.51) | 680.05 (382.78–1356.80) | 0.218 |
| IL-6, pg/mL | 0.10–2.90 | 9.91 (6.61–14.44) | 7.76 (4.44–26.33) | 10.22 (7.27–15.17) | 0.467 |
| BNP, pg/mL | 0.0–100.0 | 67.1 (28.0–165.2) | 55.3 (38.3–200.9) | 72.5 (28.9–82.7) | 0.438 |
| D-dimer, ug/mL | <0.50 | 0.74 (0.46–2.38) | 0.83 (0.54–1.96) | 0.69 (0.45–1.62) | 0.012 |
| FIB, g/L | 2.00–4.00 | 3.55 (2.81–4.80) | 3.90 (3.20–5.30) | 4.10 (3.45–6.30) | 0.026 |
| PT, s | 11.0–16.0 | 11.4 (10.6–12.3) | 11.5 (10.4–12.2) | 11.1 (10.0–12.2) | 0.060 |
| APTT, s | 27.0–45.0 | 28.1 (24.8–32.7) | 29.3 (23.7–33.1) | 23.4 (20.6–30.5) | 0.004 |
WBC white blood cell count, NC neutrophil count, LC lymphocyte count, NLR neutrophil-to-lymphocyte ratio; SaO2 oxyhemoglobin saturation, TB total bilirubin, ALT, alanine aminotransferase, AST aspartate aminotransferase, LDH lactate dehydrogenase, ESR erythrocyte sedimentation rate, CRP c-reactive protein, IL-6 interleukin-6, BNP b-type natriuretic peptide, FIB fibrinogen, PT prothrombin time, APTT activated partial thromboplastin time