Table 4.
Laboratory parameters of hypertensive and non- hypertensive COVID-19 patients without other comorbidities
| Normal range | Total (n = 225) | Nonhypertension (n = 160) | Hypertension (n = 65) | P value | |
|---|---|---|---|---|---|
| Laboratory indices | |||||
| WBC, ×109/L | 4.00–10.00 | 5.23 (3.90–7.67) | 3.25 (2.34–9.51) | 7.36 (4.86–9.73) | 0.002 |
| NC, ×109/L | 1.80–6.30 | 3.79 (2.59–6.18) | 2.52 (1.62–8.63) | 7.92 (3.43–8.86) | 0.003 |
| LC, ×109/L | 1.10–3.20 | 0.86 (0.59–1.19) | 0.54 (0.48–0.62) | 0.65 (0.40–0.85) | 0.624 |
| NLR | <5.87 | 4.63 (2.48–8.44) | 5.15 (3.03–13.81) | 14.96 (3.6–20.23) | 0.042 |
| SaO2, % | >95.0 | 96.0 (91.3–98.0) | 95.4 (91.5–98.1) | 94.8 (82.0–96.7) | 0.001 |
| TB, μmol/L | 5.10–19.00 | 11.15 (8.48–15.10) | 10.55 (8.78–13.00) | 10.60 (9.75–13.40) | 0.375 |
| ALT, U/L | <40.0 | 27.4 (17.9–48.0) | 20.0 (9.50–26.0) | 46.5 (22.3–204.8) | 0.001 |
| AST, U/L | <40.0 | 32.0 (23.0–47.3) | 36.5 (32.3–40.8) | 33.5 (25.8–94.8) | 0.060 |
| Albumin, g/L | 34.0–54.0 | 34.2 (30.5–38.1) | 28.3 (27.2–32.0) | 30.4 (29.0–32.3) | 0.008 |
| Globulin, g/L | 20.0–35.0 | 30.5 (26.1–34.6) | 29.4 (25.0–32.2) | 29.8 (26.6–32.9) | 0.129 |
| LDH, U/L | 109–245 | 286 (207–409) | 302 (250–407) | 316 (245–412) | 0.038 |
| Creatinine, μmol/L | 50.00–120.00 | 68.00 (55.50–81.35) | 76.35 (56.43–87.43) | 64.50 (54.18–110.15) | 0.090 |
| ESR, mm/h | <15.0 | 46.2 (25.3–62.5) | 42.0 (19.3–58.8) | 49.0 (25.0–77.8) | 0.160 |
| CRP, mg/L | <8.0 | 13.2 (2.9–61.7) | 44.4 (39.8–146.1) | 31.4 (16.9–96.0) | 0.011 |
| Serum ferritin, ng/mL | 21.80–275.0 | 790.52 (401.97–1324.91) | 1082.60 (617.30–1339.50) | 762.72 (533.98–1178.14) | 0.288 |
| IL-6, pg/mL | 0.10–2.90 | 9.36 (6.52–13.80) | 9.10 (5.44–34.27) | 9.62 (6.51–13.47) | 0.194 |
| BNP, pg/mL | 0.0–100.0 | 62.9 (26.6–115.8) | 73.0 (32.4–253.5) | 73.2 (30.0–127.7) | 0.877 |
| D-dimer, ug/mL | <0.50 | 0.67 (0.42–1.79) | 0.74 (0.48–2.06) | 1.09 (0.56–3.48) | 0.013 |
| FIB, g/L | 2.00–4.00 | 3.60 (2.86–4.80) | 4.35 (3.53–5.55) | 4.50 (3.83–6.25) | 0.036 |
| PT, s | 11.0–16.0 | 11.3 (10.6–12.2) | 11.5 (10.1–12.5) | 11.5 (10.0–12.5) | 0.127 |
| APTT, s | 27.0–45.0 | 28.2 (25.0–32.5) | 30.8 (26.5–33.6) | 22.3 (19.3–32.2) | 0.004 |
WBC white blood cell count, NC neutrophil count, LC lymphocyte count, NLR neutrophil-to-lymphocyte ratio, SaO2 oxyhemoglobin saturation, TB total bilirubin, ALT alanine aminotransferase, AST aspartate aminotransferase, LDH lactate dehydrogenase, ESR erythrocyte sedimentation rate, CRP c-reactive protein, IL-6 interleukin-6, BNP b-type natriuretic peptide, FIB fibrinogen, PT prothrombin time, APTT activated partial thromboplastin time