Table 4.
IELT and PEDT scores in patients with TPH2 genotypes
| SNPs | Genotypes | IELT (Median[IQR]) | PEDT (Median [IQR]) |
|---|---|---|---|
| rs11178998 | AA | 30.2 (10.5) | 16.0 (4) |
| AG | 31.7 (11.1) | 16.0 (3) | |
| GG | 32.5 (3.7) | 16.5 (6) | |
| P | 0.113 | 0.886 | |
| rs7305115 | AA | 33.2 (8.5) | 15.0 (3) |
| AG | 28.9 (11.4) | 16.0 (5) | |
| GG | 31.0 (9.5) | 16.0 (4) | |
| P | 0.103 | 0.629 | |
| SNV019 | AA | 31.4 (10.6) | 16.0 (4) |
| AG | 28.9 (9.4) | 16.0 (5) | |
| GG | - | - | |
| P | 0.064 | 0.436 | |
| rs1007023 | TT | 30.3 (10.3) | 16.0 (4) |
| GT | 30.8 (9.9) | 15.5 (5) | |
| GG | - | - | |
| P | 0.514 | 0.605 | |
| rs4290270 | AA | 32.8 (10.2) | 16.0 (3) |
| AT | 29.2 (10.5) | 15.0 (5) | |
| TT | 30.3 (9.4) | 16.0 (5) | |
| P | 0.149 | 0.638 | |
| rs17110747 | AA | 33.5 (6.2) | 18.0 (3) |
| AG | 27.4 (11.8) | 15.0 (5) | |
| GG | 31.0 (9.8) | 16.0 (4) | |
| P | 0.096 | 0.186 |
IELT = intravaginal ejaculation latency time; PEDT = premature ejaculation diagnostic tool; SNP = single-nucleotide polymorphism; SNV = single-nucleotide variant; TPH2 = tryptophan hydroxylase 2.