Table 6.
Univariate and multivariate analysis for the parameters affecting EMP2 expression in malignant tissue samples (n = 60).
| EMP2 malignant | Univariate |
#Multivariate |
||
|---|---|---|---|---|
| P | OR (95%C.I) | P | OR (95%C.I) | |
| Age (years) | 0.152 | 0.953 (0.892–1.018) | ||
| Affected lymph node | 0.146 | 0.911 (0.803–1.033) | ||
| Molecular type | ||||
| Luminal | 0.014* | 0.103 (0.017–0.628) | 0.112 | 0.148 (0.014–1.56) |
| Triple negative | 0.054 | 9.33 (0.958–90.94) | ||
| Her2 Positive | 0.304 | 3.50 (0.320–38.23) | ||
| Multicentric | 1.000 | 1.00 (0.167–5.98) | ||
| Carcinoma in situ | 0.999 | – | ||
| ER | 0.014* | 0.103 (0.017–0.628) | 0.112 | 0.148 (0.014–1.56) |
| PR | 0.014* | 0.103 (0.017–0.628) | 0.112 | 0.148 (0.014–1.56) |
| HER2/neu | 0.705 | 1.333 (0.301–5.91) | ||
| Hb (g/dl) | 0.676 | 0.878 (0.477–1.617) | ||
| WBCs ( × 10³/μl) | 0.923 | 0.980 (0.646–1.48) | ||
| Platelets ( × 10³/μl) | 0.791 | 1.002 (0.985–1.02) | ||
| CA 15–3 (IU/ml) | 0.458 | 0.953 (0.841–1.08) | ||
| EMP2 (Normal) (>0.22) | 0.715 | 0.766 (0.182–3.21) | ||
| β1-Integrin (Normal) (>0.70) | 0.715 | 1.306 (0.311–5.48) | ||
| β1-Integrin (Malignant) (≥10) | 0.033* | 5.50*(1.145–26.41) | 0.639 | 1.667 (0.198–14.054) |
$: Reference (I + II), OR: Odd's ratio, C.I: Confidence interval.
#: All variables with p < 0.1 was included in the multivariate.
*: Statistically significant at p ≤ 0.05.