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. 2020 May 18;22:100767. doi: 10.1016/j.bbrep.2020.100767

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© 2020 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 6 — Potassium currents density in cardiomyocytes isolated from Lmna^H222P/H222Pmice.

(A) Transient outward potassium current (Ito) recorded in 27 cells from wild type (WT) (black circles) and 22 Lmna^H222P/H222P cells (red circles) from 3 mice for each genotype. Current amplitude (pA) was normalized by the membrane capacitance (pF), which is an indirect measurement of cell surface.

(B) Transient ultra-rapid potassium current (IKur) recorded in 18 wild type (WT) and 15 Lmna^H222P/H222P cells from 3 mice for each genotype. Current amplitude (pA) was normalized by the membrane capacitance (pF), which is an indirect measurement of cell surface.

(C) Transient sustained potassium current (Iss) recorded in 20 wild type (WT) and 15 Lmna^H222P/H222P cells from 3 mice for each genotype. Current amplitude (pA) was normalized by the membrane capacitance (pF), which is an indirect measurement of cell surface.

(D) Membrane capacitance. The number of cardiomyocytes is indicated. (t-test).