Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Apr 7;94(5):1561–1573. doi: 10.1007/s00204-020-02720-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — Interaction of Cu compounds with THP-1 cells. Concentration of copper associated with differentiated THP-1 cells after 24-h exposure to the equitoxic (EC₂₀) concentrations of CuO NPs and CuSO₄ (a). Asterisks show the statistically different values (p < 0.001). Representative confocal microscopy images of differentiated THP-1 macrophages exposed to equitoxic concentrations (24-h EC₂₀) of Cu compounds for 24 h (b). Cell membranes were stained with Cell Mask Orange (yellow) and cell nucleus with DAPI (blue). Nanoparticles were visualized in red using reflective mode of the microscope. The arrows indicate the cellular localisation of the CuO NPs (color figure online)