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. 2019 Feb 12;93(4):1095–1139. doi: 10.1007/s00204-019-02400-1

Table 17.

Relative organ weights in male and female Wistar Han RCC rats in the combined chronic toxicity/carcinogenicity feeding trial with GM maize NK603 at an inclusion rate of 11 and 33% in the diet (at t = 12 months)

Organ Relative organ weights (organ weight/body weight × 100)
33% Control 11% NK603 33% NK603 11% NK603 + Roundup 33% NK603 + Roundup
Male rats
 Adrenal glands 0.009 ± 0.001 0.009 ± 0.001 0.009 ± 0.001 0.008 ± 0.001 0.009 ± 0.001
 Brain 0.38 ± 0.03 0.40 ± 0.05 0.39 ± 0.04 0.37 ± 0.04 0.39 ± 0.04
 Epididymides 0.22 ± 0.02 0.24 ± 0.03a 0.22 ± 0.03 0.21 ± 0.03 0.23 ± 0.03
 Heart 0.20 ± 0.01 0.21 ± 0.02 0.22 ± 0.02 0.20 ± 0.01 0.20 ± 0.01
 Kidneys 0.45 ± 0.04 0.47 ± 0.04 0.48 ± 0.08 0.45 ± 0.05 0.45 ± 0.04
 Liver 2.10 ± 0.19 2.08 ± 0.21 2.11 ± 0.14 2.09 ± 0.12 2.01 ± 0.20
 Spleen 0.17 ± 0.02 0.17 ± 0.01 0.18 ± 0.02 0.17 ± 0.03 0.17 ± 0.02
 Testes 0.64 ± 0.05 0.69 ± 0.08 0.65 ± 0.08 0.65 ± 0.06 0.68 ± 0.08
Female rats
 Adrenal glands 0.019 ± 0.003 0.019 ± 0.002 0.019 ± 0.003 0.020 ± 0.003 0.020 ± 0.003
 Brain 0.59 ± 0.06 0.65 ± 0.07a 0.64 ± 0.07a 0.64 ± 0.06a 0.65 ± 0.04a
 Heart 0.25 ± 0.02 0.26 ± 0.02 0.27 ± 0.03 0.26 ± 0.02 0.26 ± 0.02
 Kidneys 0.48 ± 0.05 0.51 ± 0.04 0.50 ± 0.05 0.52 ± 0.05a 0.52 ± 0.04a
 Liver 2.01 ± 0.19 2.05 ± 0.18 2.02 ± 0.15 2.06 ± 0.11 2.06 ± 0.15
 Ovaries 0.018 ± 0.006 0.019 ± 0.003 0.021 ± 0.004 0.021 ± 0.007 0.021 ± 0.006
 Spleen 0.20 ± 0.03 0.21 ± 0.02 0.19 ± 0.03 0.20 ± 0.03 0.22 ± 0.05
 Uterus 0.26 ± 0.06 0.28 ± 0.07 0.24 ± 0.06 0.25 ± 0.05 0.25 ± 0.05

*Statistically significant difference to the control value based on the 95% confidence interval