Table 2.

Spearman correlation between 3‐month ΔsNfL (3‐month – baseline level) and other serological, MRI, and clinical markers of possible neurotoxicity

	Correlation coefficient (95% CI)	P value
Change in GFAP (BL‐3m)	0.73 (0.43 to 0.89)	0.0018
Baseline NfL level	−0.78 (−0.80 to −0.13)	0.006
MRI Grey matter volume loss 6 months post‐IAHSCT	0.74 (0.43 to 0.89)	0.0023
Total busulfan dose	0.56 (0.14 to 0.81)	0.034
EDSS score change 6 months post‐IAHSCT	0.52 (0.086 to 0.79)	0.041
MRI whole brain volume loss 6 months post‐IAHSCT	0.58 (0.13 to 0.87)	0.045
Symbol Digit Modalities Test score change 6 months post‐IAHSCT	−0.73	0.17 (ns)
Computerized Test of Information Processing score change 6 months post‐IAHSCT	0.89	0.11 (ns)
Paced Auditory Serial Addition Test score change 6 months post‐IAHSCT	−0.36	0.15 (ns)