Figure 1.

(A) Pedigree of the family. The proband, carrier of the unbalanced reciprocal translocation (derivative of chromosome 8), indicated by the arrow, is depicted as a filled symbol to show he is affected by COE/JME. His father and sister, carriers of the balanced reciprocal translocation, shown as a small circle in the middle of the gender symbols, are filled with different gray degree intensity to signify they are respectively affected by EEG abnormalities the father (light gray) and by JME the sister (dark gray). A diagonal black and white striped quarter‐filled symbol indicates migraine with visual aura. Members genotyped in the study are asterisked. (B) Ideograms illustrating the derivative chromosomes involved in the t(4;8)(p15.2;p23.2) translocation (right), high‐resolution chromosomal GTG banding detecting the unbalanced translocation in the proband (top left) and the balanced rearrangement in his father (down left).