Table II. Proteins present in only control exosomes: top hubs of networks.
| Gene name | Protein description | # Interacting proteins |
|---|---|---|
| RHOA | Transforming protein RhoA | 21 |
| AHSG | Alpha-2-HS-glycoprotein | 14 |
| JUP | Junction plakoglobin | 13 |
| RAB5A | Ras-related protein Rab-5A | 13 |
| RAC1 | Ras-related C3 botulinum toxin substrate 1 | 13 |
| GDI2 | Rab GDP dissociation inhibitor beta | 12 |
| SPARCL1 | SPARC-like protein 1 | 12 |
| PDIA6 | Protein disulfide-isomerase A6 | 11 |
| CCT4 | T-complex protein 1 subunit delta | 10 |
| P4HB | Protein disulfide-isomerase | 10 |
| RAP1A | Ras-related protein Rap-1A (Fragment) | 10 |
| SNRNP70 | U1 small nuclear ribonucleoprotein 70 kDa | 10 |
| SPP1 | Osteopontin | 10 |
Proteins identified in only the control (YFP) exosomes were analyzed for significant enrichment (conducted as explained in experimental procedures) of protein-protein interactions by String-db. The top hub proteins with the highest number of potential protein interactors are shown here.