Table III. Shared proteins of mTau and control exosomes: top hubs of networks.
| Gene name | Protein description | # Interacting proteins |
|---|---|---|
| ACTR2 | Actin-related protein 2 | 20 |
| CDC42 | Cell division control protein 42 homolog | 19 |
| DYNC1H1 | Cytoplasmic dynein 1 heavy chain 1 | 18 |
| GNB1 | Guanine nucleotide-binding protein | 18 |
| G(I)/G(S)/G(T) subunit beta-1 | ||
| HSPA8 | Heat shock cognate 71 kDa protein | 18 |
| TF | Serotransferrin (Fragment) | 18 |
| PSMA7 | Proteasome subunit alpha type-7 | 17 |
| QSOX1 | Sulfhydryl oxidase 1 | 17 |
| TUBB4B | Tubulin beta-4B chain | 17 |
| ALDOA | Fructose-bisphosphate aldolase A | 16 |
| RAB5C | Ras-related protein Rab-5C | 16 |
Proteins present in both mTau (mutant Tau-RD-LM-YFP) and control (YFP) exosomes, shared proteins, were analyzed for significant enrichment of protein-protein interactions by String-db. The top hub proteins with the highest number of potential protein interactors are shown in this Table.