Table 4.

Prediction of pharmacokinetic properties for HA, miltefosine, amphotericin B and curcumin using SwissADME.

Compound	Molecular Weight	ESOL LogS	ESOL Class	GI Absorption	BBB Permeant	Pgp substrate	Bioavailability score
HA	316.4	-5.25	Moderately soluble	High	Yes	No	0.56
Miltefosine	407.6	-5.32	Moderately soluble	Low	No	Yes	0.55
Amphotericin B	924.1	-5.37	Moderately soluble	Low	No	Yes	0.17
Curcumin	368.4	-3.94	Moderately soluble	High	No	No	0.55

Properties determined include P-glycoprotein substrate (Pgp), Gastrointestinal absorption (GI), Blood Brain Barrier permeation (BBB), Estimated Solubility (ESOL), and Bioavailability score.