Figure 4.

Comparison of cutaneous thermal changes in different regions of interest. (A) Pre-stress thermal responses in females and males during a 2-min session of free exploration. (B) Females and males responded to restraint stress in the post-stress RS phase with an enhanced surface temperature in the head and back. Restraint stress, however, reduced cutaneous thermal responses in the tail of females. (C) Patterns of thermal responses during rearing deprivation in females post-stress RD were significantly different than those of male mice. Surface temperature in the head and back of females significantly increased whereas it decreased in the tail when compared with males. The individual bar graphs next to each panel depict the average surface temperature for each group. (D) While thermal responses in females to restraint and rearing deprivation did not differ, rearing deprivation in males reduced thermal responses in the head and back close to pre-stress levels. ^$Pre-stress vs. Post-RS and Post-RD; ^#Post-RD vs. Post-RS and Pre-stress; *p ≤ 0.05, ***p ≤ 0.000; one-way and repeated-measure ANOVA, N = 6–8/group.