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. 2020 May 25;13:83. doi: 10.3389/fnmol.2020.00083

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Copyright © 2020 Grandi, De Tomasi and Mustapha.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Subtypes of Type I change in abundance at the onset of hearing. (A) UMAP projections of Type I SGNs colored by subtypes at postnatal days 3, 8, and 12 (n = 203 single cells at P3 and n = 230 single cells at P12, representing three independent technical runs, each with four to six animals). Postnatal day 8 is reproduced from Figure 3A for clarity. (B) Quantification of the percentage of Type IA, IB, and IC cells as a fraction of the total Type I SGNs at each age. (C–H) Violin plot of (C) Lmx1a, (D) Cacna1a, (E) Kcnd2, (F) Slc4a4, (G) Fzd2, (H) Mfap4. Each point represents a single cell, colored according to its subtype or gray if outside the IA, IB, IC. On the right, a heatmap of the same data. The expression scale is giving on the right side.