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. 2020 May 25;11:502. doi: 10.3389/fgene.2020.00502

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Copyright © 2020 Liao, Bu, Xu, Jia, Chang, Liang, Jia and Lv.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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WISP1 expression with low immunocyte infiltration and no macrophage M2 polarization is associated with better UCEC prognosis. (A) WISP1 expression was weakly or not correlated with tumor purity or macrophages in UCEC using TIMER. (B) The M1 phenotype of macrophages was more highly correlated with WISP1 expression than the M2 phenotype in UCEC using GEPIA2. (C) Kaplan-Meier plotter analysis showed that UCEC patients in the WISP1-high group had longer OS and RFS than those in the WISP1-low group.