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(A) Genomic distribution of single-nucleotide variants in cancers; a majority of cancer-associated single-nucleotide variants (SNVs) [single-nucleotide polymorphisms (SNPs)] are found in the intergenic or intronic regions, and only small numbers are located in protein-coding regions of the human genome. (B) Classification of long non-coding RNA (lncRNA) transcripts; long intergenic non-protein coding RNA (lincRNA) is a major subtype of lncRNA.
