Fig. 4.

Time evolution of the Cα-RMSD and dominant conformations obtained from cluster analysis of (a) full-length m20; (b) tail-less m20; (c) full-length m5; and, (d) tail-less m5. The color scheme in the RMSD plots indicates the change of conformations, with cyan indicating the time frame for the most favored conformation, followed by crème and green as the area of the least preferred conformation, which are shown at the bottom of each RMSD plot. In each structure the red regions represent Box A, blue regions represent Box B, yellow portions represent the linker between boxes, cyan regions represent the linker between Box B and the acidic tail, and light green portions represent the acidic tail. Each conformation is shown with its corresponding percentage occupancy. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)