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. 2020 Jun 1;6(2):00356-2019. doi: 10.1183/23120541.00356-2019

TABLE 3.

Change in diffusion capacity measures per 1-sd increase in skin autofluorescence (SAF) (n=3889)

Change in diffusing capacity per 1-sd increase in SAF (95% CI) p-value
DLCO mmol·min−1·kPa−1 Model 1 −0.16 (−0.20– −0.12) <0.001
Model 2 −0.07 (−0.11– −0.03) <0.001
DLCO/VA mmol·min−1·kPa−1·L−1 Model 1 −0.02 (−0.03– −0.02) <0.001
Model 2 −0.01 (−0.02–0.00) 0.002

Model 1 adjusted for age, height and sex. Model 2 adjusted for age, height, sex, weight, smoking status (never-, ex- and current smokers), pack-years, estimated glomerular filtration rate, diabetes, log(glycated haemoglobin), log(plasma glucose) and log(C-reactive protein). DLCO: diffusing capacity of the lung for carbon monoxide; VA: alveolar volume.