Table 2.

Whole Brain Analyses: significant differences in activation for Average/low versus High Risk-taking adolescents to anticipation of big reward versus neutral contrast.

Wave 1 Average/low (N = 63) > High (N = 41) Risk-taking
Cluster Indexa	Cluster peak x, y, z	# of Voxels	Cluster Label b	p*
14	-15, -3, 16	722	Left-Caudate	.03
13	22, -62, -16	208	Right Cerebellar	.03
12	16, -82, 4	129	Right Primary Visual	.04
11	-22, -72, 2	70	Left Primary Visual	.04
10	-17, 23, 12	44	cLeft-Caudate Nucleus	.04
9	6, -74, 10	36	Right Primary Visual	.04
8	-10, -60, 50	36	Left Precuneus	.04
7	18, -36, 34	25	cPosterior Cingulate	.04
6	-16, -50, -8	22	Left-Secondary Visual	.04
5	34, -30, 28	19	cLeft-Parahippocampal	< .05
4	4, -40, 42	17	Posterior Cingulate	< .05
3	-4, -32, 62	11	Primary Motor	< .05
2	-4, -72, -2	10	Left Visual	< .05

Longitudinally Stable Average/low (N = 37) > Stable High (N = 33) Risk-Taking
Cluster Indexa	Cluster peak x, y, z	# of Voxels	Cluster Label b	p#
4	30, 32, 34	181	Right Dorsolateral Prefrontal Cortex	.052
3	-8, -60, 48	17	Left Precuneus	.071
2	4, 20, 40	15	Paracingulate Gyrus	.074

^aCluster index identified using fsl command cluster that identified peak clusters in volume, index 1 not reported due to number of voxels = < 3, clusters plotted on MNI brain in Fig. 1, Fig. 2.

^bTo identify region for cluster label, we used a combination of reverse inference on neurosynth.org/locations to identify top association with cluster activation and cross-referenced with FSL Harvard-Oxford Cortical Structural Atlas.

^cImplies regional association, due to peak being in white matter.

^*Probability α < .05 used to threshold results of TFCE output from randomize.

^#Lowered α < .08 used to threshold results of TFCE output from randomise (< .05, results null).