Table 2.

List of some animal models for NADPH oxidase research.

Target	Tool
	knock out animal	knock in animal	Loss of function mutants
Nox1	Mouse [15] Mouse floxed [16] Zebrafish [17]
Nox2	Mouse full ko [18] Mouse floxed [19] Zebrafish [17]
Nox3			Mouse [20,21] Mouse [22]
Nox4	Mouse full and floxed [23]
Nox5	Rabbit [24,25] Zebrafish [17]	Mouse [25,26]
DUOX1	Zebrafish [27] Mouse [28]
DUOX2			Mouse [29]
DuoxA1&2	Mouse floxed [30]
p22phox	Mouse floxed [31]		Mouse [32] mouse [33,34] + tyrosinase(−/−) rat [35]
p47phox	Mouse [36]	Mouse [37]	Rat [38] Mouse [39]
NoxO1	Mouse [40]
p67phox	Mouse [41]		Rat [42]
NoxA1	Mouse floxed [43]		Mouse [44]
p40phox	Mouse [45]		Mouse [46]